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Trials designed to inform clinical practice in the real world are known as pragmatic trials. They are typically characterized by a focus on the practical aspects of study design, including recruitment and consent in adherence, as well as the use of routinely available equipment.

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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which utilized a variety of investigators and included participants from different geographic areas. This type of heterogeneity is essential for practical trials to be valid and also helps to reduce the chance of bias in the results. A high degree of heterogeneity, however could cause issues with the trial design.

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The aim of pragmatic trials is to mimic real-life scenarios and 프라그마틱 슬롯버프 정품확인방법 (Highly recommended Online site) to achieve the highest level of validity externally. They are usually requested by practitioners and policymakers in order to guide their decisions. They also provide a useful method of determining the causality between an intervention and its results. They should not, however, be used to replace explanatory studies.

The idea of pragmatism is controversial and there are concerns about whether pragmatic trials should be used to replace explanation tests or if they should serve as a complement to them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which prove the validity of a clinical or physiological hypothesis as well as pragmatic trials that inform policy and practice decisions. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the traits of a pragmatic research study, including recruitment, design, delivery of the intervention, and follow-up.

There is an encouraging trend in the number of pragmatic trials that have been published. A recent Medline search using the terms pragmatic and naturalistic, restricted to controlled trials that are randomized (RCTs) produced 34 articles, as shown in red in Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatism. However, 슬롯 it is important to note that the majority of these studies were conducted in primary care settings.